Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition

By Irving W. Wainer, Krzysztof Jóźwiak, W. John Lough

This third edition has been updated to cover all aspects of chiral drugs from the academic, governmental, industrial, and clinical perspectives. New topics include the use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery, how stereochemistry impacts decisions made in the absorption, distribution, metabolism, excretion, and toxicity (ADMET) stages of drug discovery, and issues faced during the final stages of the drug development process. It also discusses the impact of International Conference on Harmonisation (ICH) on the use of single isomer drugs, chiral switches, molecular chiral recognition, and legal perspectives.

• Format: Hardcover
• Language: English
• ISBN: 1420092383
• ISBN13: 9781420092387
• Release Date: April 2012
• Publisher: CRC Press
• Length: 330 Pages
• Weight: 1.90 lbs.
• Dimensions: 1.0" x 6.1" x 9.1"