Drug Metabolism and Pharmacokinetics Quick Guide

By Cornelis E.C.A. Hop, Siamak Cyrus Khojasteh, Harvey Wong, et al.

Book Overview

Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.

• Format: Paperback
• Language: English
• ISBN: 144195628X
• ISBN13: 9781441956286
• Release Date: April 2011
• Publisher: Springer
• Length: 214 Pages
• Weight: 0.55 lbs.
• Dimensions: 0.5" x 4.9" x 7.9"