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All the functions of DNA depend on interactions with proteins. These protein interactions can be non-specific, or the protein can bind specifically to a single DNA sequence. Enzymes can also bind to DNA and of these, the polymerases that copy the DNA base sequence in transcription and DNA replication are particularly important. This book studies Interactions of DNA with proteins including DNA-binding domain, signal transduction, nuclease, DNA ligase, replication fork, and helicase.
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