Dipeptidyl Peptidase IV (CD26) in Metabolism and the Immune Response (Molecular Biology Intelligence Unit)

By Fleischer

In this book, leading experts in their field describe the enzymology and molecular biology of dipeptidyl peptidase IV/CD26 and its functions in metabolism and immune responses. CD26 is identical to the proteolytic enzyme dipeptidyl peptidase IV expressed in a variety of different tissues including epithelia and lymphocytes. CD26 binds and transports adenosine desaminase selectively in different tissues. It is also involved in T cell activation, providing stimulatory and co-stimulatory signals. It is a receptor for collagen and may be a marker for malignancy. Recent progress from a number of laboratories has shown that CD26/dipeptidyl peptidase IV plays a pivotal role in the response of T lymphocytes and may be involved in the pathogenesis of AIDS.

• Format: Hardcover
• Language: English
• ISBN: 3540601996
• ISBN13: 9783540601999
• Release Date: July 1996
• Publisher: Springer
• Length: 202 Pages
• Weight: 1.74 lbs.