Development of Selective Dna-Interacting Ligands: Understanding the Function of Non-Canonical DNA Structures

By Sefan Asamitsu

Book Overview

1. General Introduction.- 2. Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats.- 3. Ligand-Mediated G-Quadruplex Induction in a Double-Stranded DNA Context by Cyclic Imidazole/Lysine Polyamide.- 4. Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.

• Format: Hardcover
• Language: English
• ISBN: 9811577153
• ISBN13: 9789811577154
• Release Date: September 2020
• Publisher: Springer
• Length: 111 Pages
• Weight: 0.79 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"