Design and Analysis of Quality of Life Studies in Clinical Trials

By Diane L. Fairclough

Using SAS, SPSS, and R, this book addresses design and analysis aspects in enough detail so that readers can apply statistical methods to their own longitudinal studies. This edition includes a new chapter on testing models that involve moderation and mediation, a new chapter on QALYs and QTWiST specific to clinical trials, and recent methodological developments for the analysis of trials with missing data. It also presents revised discussions of multiple comparisons procedures that focus on the integration of HRQoL outcomes with other study outcomes using gatekeeper strategies. Data sets, examples, applications, and SAS, R, and SPSS code are available on the book's website.

• Format: Hardcover
• Language: English
• ISBN: 1420061178
• ISBN13: 9781420061178
• Release Date: January 2010
• Publisher: CRC Press
• Length: 424 Pages
• Weight: 1.70 lbs.
• Dimensions: 1.1" x 6.2" x 9.3"