Design and Analysis of Cross-Over Trials (Chapman & Hall/CRC Monographs on Statistics & Applied Probability)

By Byron Jones and Michael G. Kenward

Book Overview

The first edition of Design and Analysis of Cross-Over Trials quickly became the standard reference on the subject and has remained so for more than 12 years. In that time, however, the use of cross-over trials has grown rapidly, particularly in the pharmaceutical arena, and researchers have made a number of advances in both the theory and methods applicable to these trials. Completely revised and updated, the long-awaited second edition of this classic text retains its predecessor's careful balance of theory and practice while incorporating new approaches, more data sets, and a broader scope. Enhancements in the second edition include: A new chapter on bioequivalence Recently developed methods for analyzing longitudinal continuous and categorical data Real-world examples using the SAS system A comprehensive catalog of designs, datasets, and SAS programs available on a companion Web site at www.crcpress.com The authors' exposition gives a clear, unified account of the design and analysis of cross-over trials from a statistical perspective along with their methodological underpinnings. With SAS programs and a thorough treatment of design issues, Design and Analysis of Cross-Over Trials, Second Edition sets a new standard for texts in this area and undoubtedly will be of direct practical value for years to come.

• Format: Hardcover
• Language: English
• ISBN: 0412606402
• ISBN13: 9780412606403
• Release Date: January 2003
• Publisher: Chapman and Hall/CRC
• Length: 408 Pages
• Weight: 1.55 lbs.
• Dimensions: 9.0" x 1.0" x 6.3"