Epigenetic Regulation of Lymphocyte Development

By Cornelis Murre

Book Overview

Preface.- Roles of lineage-determining transcription factors in establishing open chromatin - lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.- Subject Index

• Format: Paperback
• Language: English
• ISBN: 3642447678
• ISBN13: 9783642447679
• Release Date: February 2014
• Publisher: Springer
• Length: 194 Pages
• Weight: 0.64 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"