Therapeutic Kinase Inhibitors

By Ingo K. Mellinghoff

Book Overview

Preface.- Fundamentals.- Setting up a Kinase Discovery and Development Project.-Drug Efficacy Testing in Mice.- Kinase Targets and Disease.- Gastrointestinal Stromal Tumors (GISTS).-EGFR-Mutant Lung Cancer.- Targeting Oncogenic BRAF in Human Cancer.- Beyond BRAF in Melanoma.- JAK-mutant Myeloproliferative Neoplasms.- Will Kinase Inhibitors Make It as Glioblastoma Drugs?.- Perspectives.- Predictive Genomic Biomarkers.- Epigenetic Biomarkers.- Adjuvant Trials of Targeted Agents: The Newest Battleground in the War on Cancer.- Subject Index

• Format: Paperback
• Language: English
• ISBN: 3642445802
• ISBN13: 9783642445804
• Release Date: April 2014
• Publisher: Springer
• Length: 234 Pages
• Weight: 0.77 lbs.
• Dimensions: 0.5" x 6.1" x 9.2"