Over the last decade, there has been a significant increase in available knowledge in the specialty of otorhinolaryngology-head and neck surgery with a remarkable development in diagnostic and therapeutic modalities. As a result of continuous advances in digital technologies, their integration into clinical practice has become a notable trend. This Reprint, entitled "Current and Future Trends in Otorhinolaryngology-Head and Neck Surgery," aims to provide readers with the latest developments in the field of otorhinolaryngology-head and neck surgery and underscore current and future trends. The included contributions cover a wide range of topics reflecting both clinical innovation and translational research.