Cremonello's Return is the sequel to the first novel Cremonello, which covered Thomas Cromwell's family background, youth and early adventures in Europe. He is now aged 22 and returns to London a wanted man. Until he can gain his pardon he retains his Florentine identity as Cremonello, envoy of The Frescobaldi Company.
Cromwell is pursued by his bitter enemies from the first novel: The Lomellini family from Genoa, who are becoming dominant in the textile trade across southern EnglandGeneral Bartolomeo D'Alviano, the mercenary leader maimed by Cromwell during the Battle of Garigliano in 1503.He builds his London reputation in trade and law while returning regularly to visit his mistress Maddalena de Medici, who now runs the Salon Marchesa, Rome's most prestigious venue for courtesans and gaming.
With his friend Daniele de Bossi, the Florentine Ambassador to the Court of King Henry Tudor, Cremonello and his guards transport to London multiple boxes of secret records from the Salon Marchesa. These Marchesa Archives were built up over thirty years by the salon founder, Daniele's mother Valeria, and contain inflammatory details of the sexual behaviour and gambling habits of several members of the Vatican and much of Rome's nobility. On Cremonello's return to Italy in 1508, the Lomellini immediately kidnap Maddalena and their young son Giovanni Battista. To save them, Cromwell turns himself in to the Lomellini, who transport him to Genova to apply their own brand of justice. He escapes at the last moment thanks to Ottoman allies of his old comrade Amin al Bagrahbi. Added to Cromwell's list of adversaries are now Sanxit Praesidio, the secret Vatican force of elite agents, who are active in London attempting to seize these Marchesa Archives.