Computational Neuroscience Models of the Basal Ganglia

By Ahmed A. Moustafa and V. Srinivasa Chakravarthy

Book Overview

Part 1: Modeling Basal Ganglia.- Introduction.- Basal Ganglia neurobiology.- Functions of Basal Ganglia.- Computational approaches to Basal Ganglia.- Principles of Reinforcement Learning.- The Basal ganglia as an Exploration Engine.- Spiking neuron and biophysical network models of BG with GEN dynamics.- Part 2: Modeling the Functions of Basal Ganglia.- A model of the role of basal ganglia in reaching movements.- A model of the role of basal ganglia in precision grip performance.- A model of the role of basal ganglia in spatial navigation.- A model of the role of basal ganglia in saccade generation.- A model of the role of basal ganglia in gait control.- A model of the role of basal ganglia in working memory.- A model of the role of basal ganglia in action selection.- Part 3: Modeling the action of Neuromodulators in Basal Ganglia.- A model of interaction between dopamine and serotonin in risk-based decision making.- Modeling the joint roles of dopamine and acetylcholine in the striatum.- Modeling the role of norepinephrine in exploratory behaviour.- Part 4: Applications.- Modeling the effects of Deep Brain Stimulation Parkinsonian motor and cognitive symptoms.- Modeling the effects of L-Dopa and dopamine agonists on Parkinsonian motor symptoms.- Modeling the role of the basal ganglia in schizophrenia.- Modeling the role of the basal ganglia in addiction.

• Format: Paperback
• Language: English
• ISBN: 9811341680
• ISBN13: 9789811341687
• Release Date: December 2018
• Publisher: Springer
• Length: 296 Pages
• Weight: 0.97 lbs.
• Dimensions: 0.7" x 6.1" x 9.2"