
The purpose of Volume 12 is to provide a comprehensive overview of the field of chemical and radiation carcinogenesis with particular emphasis on molecular mechanisms. The actions of various chemical carcinogens as well as ultraviolet and ionizing radiation are discussed in the...

This volume contains a comprehensive review of basic cardiovascular anatomy, physiology, and pharmacology as well as a detailed analysis of the various classes of compounds affecting the heart and blood vessels. Cardiovascular biology will include embryologic development, physiology,...

This volume reviews our current understanding of the hematopoietic system and toxic effects on its components. The work is arranged in six parts. The first provides a background on hematotoxicology, describes the components of blood and blood-forming organs and reviews the complex...

Volume 5 provides current knowledge regarding the intricacies of the immune system and the manner by which environmental agents can disrupt immune homeostasis and induce pathologies. The volume begins with an introduction to the field of immunotoxicology and an overview of the...

Neurotoxicology is among the fastest growing of the toxicological disciplines. Recent refinements of neuropathologic techniques, meticulous validation of behavioral tests, and introduction of the tools of molecular biology have led to rapid progress in our understanding of the...


Volume 8 begins with a detailed description of the functional anatomy of the various regions and critical cells of the respiratory tract, from the nasal cavity to the gas exchange region. This section conveys the structural heterogeneity of the respiratory system and how it determines...

Comprehensive Toxicology - the first comprehensive reference work in toxicology, is an in-depth, state-of-the-art review of toxicology of unrivalled quality. It is designed to encompass investigation from a molecular level to the intact organism. Presented in a 13-volume printed...