The colloidal gold probe is the most recent immunocytochemical marking technique to have been developed for the detection of antigens in situ. The major advantages of colloidal gold probes are that they are small, dense probes of wide applicability in the biological sciences. The probe can be used for the localization of specific proteins in conjunction with a wide range of microscopical and non-microscopical techniques. This book aims to describe the established techniques of gold probe production and immunolabelling. Each technique is summarized in a table which can be used in the laboratory without recourse to the text. Original references are also given to enable readers to trace the origins of each technique. The book can therefore be used both as a bench-top manual and as a guide to further reading.
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