Coconut Oil And Vitamin D Supplementation In Knee

By Velangi Monal Rajendra Leena

Introduction: The increasing global prevalence of Knee OA suggests a strong need to

control various risk factors of its occurrence as well as progression. The present study

is an attempt to assess the effect of vitamin D and Virgin Coconut Oil (VCNO) in

Knee osteoarthritis (KOA).

Methods: After obtaining the ethical clearance, the study was conducted in two

phases. In Phase I, 300 KOA patients were screened for vitamin D status and 270

patients with low serum vitamin D level were selected purposively from K.J. Somaiya

Medical College Hospital and Research Centre, Mumbai. They were assessed for stage

of KOA, clinical signs and symptoms, anthropometric measures (BMI, WHR) and

body composition (Total body fat, BMD, LBM using BIA), bone turnover (serum

vitamin D, calcium and phosphorus), inflammatory markers (CRP, ESR), pain and

functional abilities (VAS, WOMAC and 6-MWT); dietary energy and nutrient intake,

and dietary patterns using standard techniques. Based on the results, suitable diet and

exercise guidelines were suggested. For Phase 2 of the study, 100 early KOA

participants from phase 1were selected purposively and divided into 2 groups (E1 and

E2). A 12 week intervention was carried out during which E1 received Vitamin

D3 (n=50) and E2- Vitamin D3 and VCNO (n=50) supplementation. Postintervention

all the parameters were reassessed along with sCOMP in a sub sample

(n=80). Data was analyzed using SPSS 16.0.

• Format: Paperback
• Language: English
• ISBN: 9204003863
• ISBN13: 9789204003864
• Release Date: December 2022
• Publisher: Independent Author
• Length: 198 Pages
• Weight: 0.65 lbs.
• Dimensions: 0.4" x 6.0" x 9.0"