Chromosome Structural Analysis: A Practical Approach

By Wendy Bickmore

In eukaryotes, DNA is packaged in chromosomes, the structure and number of which provide a great deal of information for many aspects of cellular genetics. This hands-on guide is an up-to-date survey of experimental methods for analyzing chromosome structure, and it includes techniques for vertebrates, Drosophila, yeast, and Xenopus. Organized in a methodical fashion, the book begins with the analysis of chromatin and protein mapping, followed by chapters on whole chromosome structure, then on whole-mount tissues and the analysis of sub-structure in mammals, and concluding with two chapters on the experimental manipulation of chromosome structure. With over 70 protocols, the book will be invaluable for a wide range of researchers in genetics, medicine, and molecular biology.

• Format: Hardcover
• Language: English
• ISBN: 0199636990
• ISBN13: 9780199636990
• Release Date: July 1999
• Publisher: Oxford University Press, USA
• Length: 234 Pages
• Weight: 1.20 lbs.
• Dimensions: 0.7" x 6.3" x 9.3"