Chromosomal Instability in Cancer Cells

Book Overview

DNA Repair and Chromosomal Translocations.- CINcere modelling: What have mouse models for chromosome instability taught us?.- Telomere Dysfunction, Chromosomal Instability and Cancer.- Genetic Instability and Disease Prognostication.- Causes of Chromosomal Instability.- Patterns of Chromosomal Aberrations in Solid Tumors.- Yeast as Models of Mitotic Fidelity.- The diverse effects of complex chromosome rearrangements and chromothripsis in cancer development.- Consequences of aneuploidy in cancer: transcriptome and beyond.

• Format: Paperback
• Language: English
• ISBN: 3319349627
• ISBN13: 9783319349626
• Release Date: October 2016
• Publisher: Springer
• Length: 224 Pages
• Weight: 0.73 lbs.
• Dimensions: 0.5" x 6.1" x 9.2"