Catalysis in Asymmetric Synthesis

By Jonathan M. J. Williams and Vittorio Caprio

Catalysis in Asymmetric Synthesis, 2nd Edition

Asymmetric synthesis has become a major aspect of modern organic chemistry. The stereochemical properties of an organic compound are often essential to its bioactivity, and the need for stereochemically pure pharmaceutical products is a key example of the importance of stereochemical control in organic synthesis. However, achieving high levels of stereoselectivity in the synthesis of complex natural products represents a considerable intellectual and practical challenge for chemists.

Written from a synthetic organic chemistry perspective, this text provides a practical overview of the field, illustrating a wide range of transformations that can be achieved. The book captures the latest advances in asymmetric catalysis with emphasis placed on non-enzymatic methods.

Topics covered include:

Reduction of alkenes, ketones and imines Nucleophilic addition to carbonyl compounds Catalytic carbon-carbon bond forming reactions Catalytic reactions involving metal carbenoids Conjugate addition reactions

Catalysis in Asymmetric Synthesis bridges the gap between undergraduate and advanced level textbooks and provides a convenient point of entry to the primary literature for the experienced synthetic organic chemist.

• Format: Paperback
• Language: English
• ISBN: 1405175192
• ISBN13: 9781405175197
• Release Date: March 2009
• Publisher: Wiley-Blackwell
• Length: 408 Pages
• Weight: 1.30 lbs.
• Dimensions: 0.9" x 5.9" x 8.9"