Cancer Chemotherapy & Biological Response Modifiers Annual 22 contains an expanded section on Melanoma, special detail is included regarding advances in screening, prevention and predisposition for this increasingly frequent disease. Annual 22 also includes updates on biology and treatment of common malignancies as well as chapters that summarise recent advances in chemotherapy and immunotherapy for cancer.The section on drugs includes new chapters on the clinical use of epidermal growth factor receptor pathways and on angiogenesis pathway inhibitors. These agents have moved rapidly from preclinical models to demonstrated clinical efficacy and are becoming part of comprehensive oncologic care.The section on tumours provides detailed updates on past year's advances in the understanding of risk, classification, staging and management of common malignancies.The section on biologics provides chapters on active immunotherapy through vaccines or cytokine administration, exciting perspectives on the modification of T cells to recognise tumours using tumour-reactive monoclonal antibody, and an important review detailing the effect of conventional cancer treatment on the patient's immune system.The special section within Annual 22 is devoted to recent advances in the understanding and treatment of melanoma. Special detail is included regarding advances in screening, prevention and predisposition for this increasingly frequent disease, in addition to chapters on surgical treatment and biologic response modifiers interventions. Chapters on the uses of interferon, and on other cytokines combined with chemotherapy, summarise how and when these approaches have proven to be useful. Four chapters then review separate classes of immunologic interventions for melanoma.
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