When two young braves were killed for a wild stallion they had caught, the Cherokee warriors went on the warpath and began killing all Caucasian settlers across the outer plains. The instant the U.S president heard about the native's uprise, he dispatched the cavalry to put a stop to the torment. The cavalrymen hunted down and killed many Cherokee warriors. Following their defeat, the Cherokee tribe was struck with massive sanctions by the government, that protruded them from committing such acts in the future.
Despite the sanctions, many years later the son of one of the two Indians killed for their captured horse, got into a dispute with the son of the businessman who killed his father. To get his revenge, the Cherokee warrior fought and killed the businessman's son, in a fair fight. When the xenophobic businessman learnt about his son's killing, he sent his gunners to pretend they were Indians on the warpath, so the U.S cavalrymen could get involved. Once the Cherokee warriors heard the cavalrymen had been deployed to render judgements and arrests against them, they decided to flee the country to Mexico. With a mixed army of soldiers and bigot cowboys in pursuit, the Cherokee tribe must reach the border and cross into Mexico, or risked being anahilated.