Biopacemaking

Book Overview

Biopacemaking: Clinically Attractive, Scientifically a Challenge.- Embryological Development of Pacemaker Hierarchy and Membrane Currents Related to the Function of the Adult Sinus Node: Implications for Autonomic Modulation of Biopacemakers.- Creation of a Biological Pacemaker by Gene- or Cell-Based Approaches.- Creating a Cardiac Pacemaker by Gene Therapy.- Biological Pacemakers Based on If.- Gene Therapy to Create Biological Pacemakers.- Inhibition of Cardiomyocyte Automaticity by Electrotonic Application of Inward Rectifier Current from Kir2.1 Expressing Cells.- Propagation of Pacemaker Activity.- Computer Modelling of the Sinoatrial Node.- Application of Mesenchymal Stem Cell-Derived Cardiomyocytes as Bio-pacemakers: Current Status and Problems to Be Solved.- Enrichment of Cardiac Pacemaker-Like Cells: Neure gulin-1 and Cyclic amp Increase If-Current Density and Connexin 40 mRNA Levels in Fetal Cardiomyocytes.

• Format: Paperback
• Language: English
• ISBN: 364209127X
• ISBN13: 9783642091278
• Release Date: November 2010
• Publisher: Springer
• Length: 182 Pages
• Weight: 0.61 lbs.
• Dimensions: 0.4" x 6.1" x 9.2"