Biology, Computing, and the History of Molecular Sequencing: From Proteins to Dna, 1945-2000

By Miguel García-Sancho

Book Overview

Introduction: An Historical Approach to Sequencing PART I: EMERGENCE: FREDERICK SANGER'S PIONEERING TECHNIQUES (1943-1977) The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943-1962) From Chemical Degradation to Biological Replication (1962-1977) PART II: MECHANISATION - 1: COMPUTING AND THE AUTOMATION OF SEQUENCE RECONSTRUCTION (1962-1987) Sequencing Software and the Shift in the Practice of Computation Sequence Databases and the Emergence of 'Information Engineers' PART III: MECHANISATION - 2: THE SEQUENCER AND THE AUTOMATION OF SEQUENCE CONSTRUCTION (1980-2000) A New Approach to Sequencing at Caltech The Commercialisation of the DNA Sequencer Conclusions: A Long History of Practices Appendix 1: Oral Histories Appendix 2: Archival Sources Notes Bibliography

• Format: Paperback
• Language: English
• ISBN: 1349321222
• ISBN13: 9781349321223
• Release Date: January 2012
• Publisher: Palgrave MacMillan
• Length: 242 Pages
• Weight: 0.67 lbs.
• Dimensions: 0.6" x 5.5" x 8.5"