Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches

Book Overview

1. Manufacturing (methods) and characterization (with respect to

size, shape, surface properties, coatings, charge etc.) of materials

1.1 Metal and oxide nanoparticles (Au, Ag, ZnO, SPIOs, Silica.....)

(M. Epple et al., C. Graf, E. R?hl, St. Barcikowski)

1.2 Quantum dots and quantum rods

(A. Eychm?ller, H. Weller et al. )

1.3 Carbon nano tubes

(M. Kappes, KIT)

1.4 Polymer particles

(K. Landfester et al.)

1.5 Surface functionalized and complex ligand shell particles

(W. Parak et al.)

1.6 Stability of NP emulsions and particle agglomeration

(M. Maskos, M. Epple, H. Hoffmann (EPFL Lausanne))

2 Interactions of nanoparticles with proteins

2.1 Formation, growth dynamics and stabilities of protein coronae

(G. U. Nienhaus et al.)

2.2 Protein selectivity in protein adsorption

(R. Tenzer, R. Stauber)

2.3 The biological significance of protein coronae

(Iseult Lynch (U. Birmingham) et al.)

3 Membrane transfer mechanisms, cellular uptake and intracellular trafficking of nanoparticles

3.1 Transport across air-liquid interfaces

(C.M. Lehr, Helmholtz-Institut f?r Pharma. Forsch., Saarbr?cken, H.J. Galla, M?nster)

3.2 Cellular uptake mechanisms (including adhesive interactions and

3D Fluorescence Microscopy)

(B. Rothen et al., G.U. Nienhaus)

3.3 The role of particle surface charge and membrane elasticity in membrane

transfer

(A. Janshoff et al. (G?ttingen), A. Wixforth (Augsburg), A. Reller (Ulm))

3.4 Localization in cells and sub-cellular compartments using state-of-

the-art imaging techniques incl. super-resolution microscopy

(E. R?hl, C. Graf.....)

4 Cellular responses and health effects

4.1 Cellular defense, ROS formation and cytotoxicity

(V. Stone, Heriot-Watt Edinburgh)

4.2 The inflammasome

(K. Landfester, V. Mail?nder)

4.3 Interactions with lung cells, fate and translocations

(B. Rothen et al. Fribourg (CH))

4.4 Interactions with skin cells and skin

(J. Lademann et al.)

4.5 Fate and translocations in GI track

(A. Frey (Borstel), P. Nielsen, Hamburg)

4.5 Nanomedicine

• Format: Paperback
• Language: English
• ISBN: 3030124630
• ISBN13: 9783030124632
• Release Date: October 2020
• Publisher: Springer
• Length: 344 Pages
• Weight: 1.13 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"