Doug Varney (Sam Rockwell) is the model of suburban respectability-until the night he delivers a prescription to the home of Elizabeth Roberts (Olivia Wilde). Gorgeous, seductive and multiply addicted, Elizabeth eagerly introduces Doug to extra-large martinis, uninhibited bedroom behavior and the illicit pleasures of the pharmacopeia he has access to in his store. Disregarded for years by everyone from his domineering wife Kara (Michelle Monaghan)...