As we learn more about the the basic mechanisms of headache, it becomes obvious that they are indeed complex, and that no single factor will ever be found which alone can explain migraine or other primary headaches. It is imperative to improve the classification and diagnostic criteria of headache disorders and to study patients in a more systematic way in order to gather reliable information about physiological and biochemical abormalities occurring during headache attacks. The purpose of this book is to present anatomical, physiological and pharmacological knowledge relevant to headache along with actual studies of pathophysiological events in headache patients, thereby bridging the gap between basic science and clinical science.
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