This book constitutes the refereed proceedings of the Second International Conference on Artificial Intelligence Computing and Systems, AICompS 2025, which took place in Fukuoka, Japan, in November 26-28, 2025.
The 30 full papers and 10 short papers were included in this book were carefully reviewed and selected from 69 submissions. This conference focused on a broad range of topics spanning artificial intelligence, AI privacy and safety, secure and trustworthy AI systems, as well as systems, networks, hardware, and information security for AI-driven environments.