
Important clinical issues as the outcome of long term treatment withantidepressants, the time of onset of the antidepressant response andthe limitations of the antidepressants currently available are coveredin this monograph. Leading researchers in the area of clinical andexperimental...

Clinical issues.- Long-term course, comorbidity and long-term outcome in depressive disorders.- Do antidepressants really take several weeks to show effect?.- Commentary on the limitation of antidepressants in current use.- Mechanisms of action.- Mechanisms underlying the speed...