Alternative Splicing and Disease

By Philippe Jeanteur and Jeanteur, Philippe ,

Book Overview

Methods and Platforms for the Quantification of Splice Variants' Expression.- Pre-mRNA Missplicing as a Cause of Human Disease.- Alternative Splicing: Therapeutic Target and Tool.- SR Proteins as Potential Targets for Therapy.- Misregulation of Tau Alternative Splicing in Neurodegeneration and Dementia.- Spinal Muscular Atrophy and Therapeutic Prospects.- Misregulation of Alternative Splicing Causes Pathogenesis in Myotonic Dystrophy.- Redirecting Splicing to Address Dystrophin Mutations: Molecular By-pass Surgery.- Altered Splicing in Prelamin A-Associated Premature Aging Phenotypes.- Splicing Modulation as a Modifier of the CFTR Function.

• Format: Paperback
• Language: English
• ISBN: 3642070817
• ISBN13: 9783642070815
• Release Date: November 2010
• Publisher: Springer
• Length: 257 Pages
• Weight: 0.85 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"