Advances in Medicinal Chemistry: Volume 5

Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.

• Format: Hardcover
• Language: English
• ISBN: 0762305932
• ISBN13: 9780762305933
• Release Date: January 2000
• Publisher: Elsevier Science
• Length: 200 Pages
• Weight: 1.01 lbs.
• Dimensions: 0.5" x 6.3" x 9.2"