Multichain Immune Recognition Receptor Signaling: From Spatiotemporal Organization to Human Disease

Book Overview

Immunological recognition is a central feature of the adaptive immunity of vertebrates. With the exception of agnathans, which developed an entirely distinct set of immunologically-specific molecules, all vertebrates use a recognition system based on what Achsah Keegan and I suggested in 1992 be termed multichain immune recognition receptors (MIRRs). MIRRs consist of ligand-binding molecules that are immunoglobulin supergene family members associated...

• Format: Paperback
• Language: English
• ISBN: 1441918876
• ISBN13: 9781441918871
• Release Date: November 2010
• Publisher: Springer
• Length: 357 Pages
• Weight: 1.19 lbs.
• Dimensions: 0.8" x 6.1" x 9.2"