A Handbook for Dna-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery

By Robert A. Goodnow Jr.

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology.

Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:

Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry - synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

• Format: Hardcover
• Language: English
• ISBN: 1118487680
• ISBN13: 9781118487686
• Release Date: April 2014
• Publisher: Wiley
• Length: 480 Pages
• Weight: 1.80 lbs.
• Dimensions: 1.2" x 6.1" x 9.3"