We are pleased to introduce the Special Issue: "An Update on Retinal Diseases: From Diagnosis to Treatment", providing the latest novel expertise regarding the diagnosis and treatment of retinal diseases, including neovascular age-related macular degeneration, diabetic macular edema, retinal vascular occlusion, central serous chorioretinopathy, retinitis pigmentosa, and retinal degenerative side effects of drugs used for systemic diseases. The included information will aid readers within this field in better managing of patients with such pathologies.