Alzheimer's Disease: Advances in Genetics, Molecular and Cellular Biology

by Rudolph E. Tanzi

Book Overview

The Genetics of Alzheimer's Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer's Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that Mediate A? Induced Neuronal Dysfunction.- Beta Amyloid and Excitatory Synapses.- A? Degradation.- Role of A ? Transport...

• Format: Paperback
• Language: English
• ISBN: 1441941959
• ISBN13: 9781441941954
• Release Date: October 2010
• Publisher: Springer
• Length: 286 Pages
• Weight: 0.93 lbs.
• Dimensions: 0.6" x 6.1" x 9.2"