Historical Perspective In 1842, in a paper entitled "Further Development of a General Law of Vital Periodicity", which was part of a series of seven Lancet papers on periodicities in health and disease, Thomas Laycock wrote: "As everything finite must have a period within which its existence is circumscribed, so every period so circumscribing the finite, being a measure of time, must be divisible into lesser periods. But it has always been found easier...
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