Sialo-Xenoantigenic Glycobiology: Molecular Glycobiology of Sialylglycan-Xenoantigenic Determinants in Pig to Human Xenotransplantation

by Cheorl-Ho Kim and Kwon-Ho Song

Book Overview

Screening of pig glycosyltransferase genes related to xenoantigens and their masking.- Cloning and tissue specific expression of pcmah and its alternative transcripts.- Functional characterization of pCMAH in the synthesis of N-glycolylneuraminic acid as the xenoantigenic determinant in pig-to-human xenotransplantation.- Identification of two alternative promoters of the pig CMP-N-acetylneuraminic acid hydroxylase gene.- Screening for xenoantigenic...

• Format: Paperback
• Language: English
• ISBN: 3642434436
• ISBN13: 9783642434433
• Release Date: December 2014
• Publisher: Springer
• Length: 64 Pages
• Weight: 0.27 lbs.
• Dimensions: 0.2" x 6.1" x 9.2"