Genetics and Periodontal Disease

Bys: Pawar, Priyanka and Yadav, Ashish

Periodontal disease is a complex, multifactorial condition influenced by microbial, environmental, and host-related factors. Genetics plays a significant role in determining individual susceptibility, severity, and progression of the disease. Variations in genes regulating immune response, inflammatory pathways, and connective tissue metabolism-such as IL-1, TNF-α, and MMP polymorphisms-have been linked to higher risk. Family and twin studies also support a heritable component, especially in aggressive periodontitis. Understanding genetic predisposition helps in early identification of high-risk individuals, guiding personalized prevention and treatment strategies.

• Format: Paperback
• Language: English
• ISBN: 6202436301
• ISBN13: 9786202436304
• Release Date: September 2025
• Publisher: LAP Lambert Academic Publishing
• Length: 52 Pages
• Weight: 0.18 lbs.
• Dimensions: 0.1" x 6.0" x 9.0"