Cell Cycle Deregulation in Cancer

Cancer is fundamentally a disease of abnormal cell proliferation: Cancer cells multiply when and where they should not. This proliferation entails escape from normal bounds imposed by the tissue environment, the internal biology of the cell (DNA damage, chromosomal imbalances, disorganized mitotic spindles), and the proliferative history of the cell (normal generational times). Some of the key oncogenic events in cancer directly perturb proteins...

• Format: Paperback
• Language: English
• ISBN: 1461425697
• ISBN13: 9781461425694
• Release Date: May 2012
• Publisher: Springer
• Length: 206 Pages
• Weight: 0.68 lbs.
• Dimensions: 0.5" x 6.1" x 9.2"