Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations
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Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations summarizes and integrates research on the structural, neurochemical, genetic, and functional abnormalities associated with bipolar disorder in these populations. Patients with a childhood or adolescent onset of bipolar disorder typically have a more severe and genetically loaded form of the illness than adult onset patients. Relatives of bipolar disorder patients, particularly offspring of bipolar disorder parents, represent an ideal population for the study of biomarkers of risk. The book reviews biomarkers of risk using diverse translational methodologies including functional and structural neuroimaging, neuropsychological testing, and integrated genomics. Chapters also examine the interaction between genomic and environmental influences that shape behavior. Psychotherapeutic and pharmacological interventions are discussed as well as novel therapeutics that may alter disease course more effectively. Key Features, Identifies risk factors for bipolar disorder, Integrates longitudinal studies from diverse translational methodologies, Provides basic neuroscience and clinical information about bipolar disorder, Includes treatment intervention via psychotherapy and pharmacology Book jacket.
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